Services


Chemistry / Immunology

Sex Hormone Binding
Globulin (SHBG)

TEST:    SHBG (CMIA)

OTHER TEST REQUEST NAME:
• Sex Hormone Binding Globulin
• Testosterone-estrogen Binding Globulin (TeBG)

TEST COMPOSITION:
Not applicable

INTENDED USE:
May be used to help evaluate men for low testosterone and women for excess testosterone production. It may be ordered in conjunction with other tests to evaluate the status of a person's sex hormones.

METHODOLOGY:
Chemiluminescent Microparticle Immunoassay (CMIA)

LABORATORY SECTION:
Immunology

SPECIAL INSTRUCTIONS/PATIENT PREPARATIONS:
No patient preparation necessary.

COLLECTION/SAMPLE CONTAINER:
Red or Gold tube

SPECIMEN AND VOLUME REQUIREMENT
Note: Follow tube manufacturer recommendation.:     1-3 mL Serum
 

ALTERNATIVE SPECIMEN AND VOLUME REQUIREMENT:
1-3 mL Plasma (Li-Heparin, Na-Heparin, Ammonium Heparin, K-EDTA)

SPECIMEN STABILITY       
•   ROOM TEMPERATURE (15-25°C)    :    Not specified
•   REFRIGERATED TEMPERATURE (2-8°C)    :    8 Days
•   FREEZER TEMPERATURE (-20°C)    :    3 months (Freeze only once)

TRANSPORT TEMPERATURE:   
Transport specimen at 2°C – 8 °C (with cold packs)

REJECTION CRITERIA:
• Hemolyzed specimen
• Markedly lipemic specimen
• Specimen stored/transported outside the temperature range
• Quantity not sufficient
• Improperly labeled specimens

RUNNING DAY:
Wednesday

CUT OFF TIME:
12:00 MIDNIGHT

TAT/RELEASING OF RESULTS:
ROUTINE (on running days)
• 4 hours after receipt of specimen/ arrival of messenger
STAT (on running days only)
• 2½ hours from extraction/messenger arrival

REFERENCE INTERVAL / RESULT INTERPRETATION:
Male: 13.50-71.40 nmol/L
Female: 19.80-155.20 nmol/L

LIMITATIONS/INTERFERENCES:  

•    Specimens from patients who have received preparations of mouse monoclonal antibodies for diagnosis or therapy may contain human anti-mouse antibodies (HAMA). Specimens containing HAMA may produce anomalous values when tested with assay kits that employ mouse monoclonal antibodies.

•         Heterophilic antibodies in human serum can react with reagent immunoglobulins, interfering with in vitro immunoassays. Patients routinely exposed to animals or to animal serum products can be prone to this interference, and anomalous values may be observed.

•         High protein concentration on plasma samples interferes with the assay.       

@2017 Hi-Precision Diagnostics. All Rights Reserved